Safe-by-design and bioinformatics

One of the main challenges of nanotechnology lies with the development of functional and safe nanomaterials. In this context, at ITENE we work on the safe-by-design concept, which focuses on addressing the toxicological effects and potential for exposure from product inception until its end of life, to prevent possible adverse effects on health and the environment caused by the materials’ toxicological profile or by high probability of exposure during industrial use or at the consumption stage by occupational users or the general public.

Furthermore, in this context, we develop bioinformatic computational models to predict toxicological profiles at the design stage and to forecast exposure during specific uses throughout the life cycle.

Safe-by-design, assessments and predictive modelling

At ITENE, we have considerable experience in the safe-by-design concept, which involves defining safety and prevention measures during the design phase of a facility, process, material or a product. Specifically, we work in the following areas:

Applications and benefits

The application of bioinformatics and safe-by-design modelling brings many benefits and outcomes:

• Detection of toxicity or of the risks associated with micro- and nanomaterials and nanotechnology.
• Prevention of occupational hazards and protection of health.
• Obtaining safer materials and materials with improved properties.